Spas promote benefits of CBD oil, but the science isn't in yet
CBD, or cannabidiol, is a compound found in cannabis that’s becoming a huge wellness trend. Some say it can help ease pain, promote relaxation and improve …
CBD oil doesn’t work for everyone I have a relative who has rheumatoid arthritis and a bad back and she has spent close to $400 trying to figure out what works best for her
she’s tried smoking CBD bud she’s tried different milligrams it starts off at 50and it can go up to 3000 mgs Pills or tincture or bud
The only thing it did was make her very tired didn’t do anything for her.
There’s a lot of hype about it but no one talks about how expensive it really is either.
It doesn’t work for some people
I have people trying to push CBD on me and I tried it and it didn’t work for a tendon in my elbow .
I think people pushing CBD needs to understand it doesn’t work for everybody and it is very pricey that’s another thing that we need to talk about
I do have friends that it worked for it for but they used it for depression.
Big money big Pharma trying to keep it from us. I have RA and it saved my life I don’t need fake science reports paid for by pharmaceutical companies are trying to add things to it so that you need a prescription and they can make big money.I use it every day! And it doesn’t get you high . They all just want to make money CBD oil is good I have my own proof
How about some case studies. Go buy some CBD lotion, and put it on your skin. You will see that it works. Lol. You dont need some fancy institution to publish a paper to figure it out.
Original Investigation August 29, 2018 Effect of Cannabidiol on Medial Temporal, Midbrain, and Striatal Dysfunction in People at Clinical High Risk of Psychosis A Randomized Clinical Trial Sagnik Bhattacharyya, MBBS, MD, PhD1; Robin Wilson, MBBS, MRCPsych1; Elizabeth Appiah-Kusi, MSc1; et al Aisling O’Neill, MSc1; Michael Brammer, PhD2; Jesus Perez, MBBS, MD, PhD3; Robin Murray, DSc, FRCPsych, FRS1; Paul Allen, PhD1,4; Matthijs G. Bossong, PhD1,5; Philip McGuire, MD, PhD, FRCPsych1 Author Affiliations JAMA Psychiatry. Published online August 29, 2018. doi:10.1001/jamapsychiatry.2018.2309
Results Of the 16 participants in the CBD group, 6 (38%) were female, and the mean (SD) age was 22.43 (4.95) years; of 17 in the placebo group, 10 (59%) were female, and the mean (SD) age was 25.35 (5.24) years; and of 19 in the control group, 8 (42%) were female, and the mean (SD) age was 23.89 (4.14) years. Brain activation (indexed using the median sum of squares ratio of the blood oxygen level–dependent hemodynamic response effects model component to the residual sum of squares) was analyzed in 15 participants in the CBD group, 16 in the placebo group, and 19 in the control group.
Participants receiving placebo had reduced activation relative to controls in the right caudate during encoding (placebo: median, −0.027; interquartile range [IQR], −0.041 to −0.016; control: median, 0.020; IQR, −0.022 to 0.056; P < .001) and in the parahippocampal gyrus and midbrain during recall (placebo: median, 0.002; IQR, −0.016 to 0.010; control: median, 0.035; IQR, 0.015 to 0.039; P < .001). Within these 3 regions, activation in the CBD group was greater than in the placebo group but lower than in the control group (parahippocampal gyrus/midbrain: CBD: median, −0.013; IQR, −0.027 to 0.002; placebo: median, −0.007; IQR, −0.019 to 0.008; control: median, 0.034; IQR, 0.005 to 0.059); the level of activation in the CBD group was thus intermediate to that in the other 2 groups. There were no significant group differences in task performance.
Conclusions and Relevance Cannabidiol may partially normalize alterations in parahippocampal, striatal, and midbrain function associated with the CHR state. As these regions are critical to the pathophysiology of psychosis, the influence of CBD at these sites could underlie its therapeutic effects on psychotic symptoms.
CBD oil doesn’t work for everyone I have a relative who has rheumatoid arthritis and a bad back and she has spent close to $400 trying to figure out what works best for her
she’s tried smoking CBD bud she’s tried different milligrams it starts off at 50and it can go up to 3000 mgs
Pills or tincture or bud
The only thing it did was make her very tired didn’t do anything for her.
There’s a lot of hype about it but no one talks about how expensive it really is either.
It doesn’t work for some people
I have people trying to push CBD on me and I tried it and it didn’t work for a tendon in my elbow .
I think people pushing CBD needs to understand it doesn’t work for everybody and it is very pricey that’s another thing that we need to talk about
I do have friends that it worked for it for but they used it for depression.
Big money big Pharma trying to keep it from us. I have RA and it saved my life I don’t need fake science reports paid for by pharmaceutical companies are trying to add things to it so that you need a prescription and they can make big money.I use it every day! And it doesn’t get you high . They all just want to make money CBD oil is good I have my own proof
excuses
There is video of a Parkinson's patient getting immediate relief, countless ppl with seizure disorders have found peace, but this. Ugh.
How about some case studies. Go buy some CBD lotion, and put it on your skin. You will see that it works. Lol. You dont need some fancy institution to publish a paper to figure it out.
It is safe and useful. Try it
Because the "science" isn't there. JAMA https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2697762
Original Investigation
August 29, 2018
Effect of Cannabidiol on Medial Temporal, Midbrain, and Striatal Dysfunction in People at Clinical High Risk of Psychosis
A Randomized Clinical Trial
Sagnik Bhattacharyya, MBBS, MD, PhD1; Robin Wilson, MBBS, MRCPsych1; Elizabeth Appiah-Kusi, MSc1; et al Aisling O’Neill, MSc1; Michael Brammer, PhD2; Jesus Perez, MBBS, MD, PhD3; Robin Murray, DSc, FRCPsych, FRS1; Paul Allen, PhD1,4; Matthijs G. Bossong, PhD1,5; Philip McGuire, MD, PhD, FRCPsych1
Author Affiliations
JAMA Psychiatry. Published online August 29, 2018. doi:10.1001/jamapsychiatry.2018.2309
Results Of the 16 participants in the CBD group, 6 (38%) were female, and the mean (SD) age was 22.43 (4.95) years; of 17 in the placebo group, 10 (59%) were female, and the mean (SD) age was 25.35 (5.24) years; and of 19 in the control group, 8 (42%) were female, and the mean (SD) age was 23.89 (4.14) years. Brain activation (indexed using the median sum of squares ratio of the blood oxygen level–dependent hemodynamic response effects model component to the residual sum of squares) was analyzed in 15 participants in the CBD group, 16 in the placebo group, and 19 in the control group.
Participants receiving placebo had reduced activation relative to controls in the right caudate during encoding (placebo: median, −0.027; interquartile range [IQR], −0.041 to −0.016; control: median, 0.020; IQR, −0.022 to 0.056; P < .001) and in the parahippocampal gyrus and midbrain during recall (placebo: median, 0.002; IQR, −0.016 to 0.010; control: median, 0.035; IQR, 0.015 to 0.039; P < .001). Within these 3 regions, activation in the CBD group was greater than in the placebo group but lower than in the control group (parahippocampal gyrus/midbrain: CBD: median, −0.013; IQR, −0.027 to 0.002; placebo: median, −0.007; IQR, −0.019 to 0.008; control: median, 0.034; IQR, 0.005 to 0.059); the level of activation in the CBD group was thus intermediate to that in the other 2 groups. There were no significant group differences in task performance.
Conclusions and Relevance Cannabidiol may partially normalize alterations in parahippocampal, striatal, and midbrain function associated with the CHR state. As these regions are critical to the pathophysiology of psychosis, the influence of CBD at these sites could underlie its therapeutic effects on psychotic symptoms.
The Almighty 🌿 herb.
No big massive money in CBD oil for the petrochemical pill company's to profit off of.
Science isn’t there because it’s been a crime to study a plant…stupid!
You mean how the Democrats are trying to figure out how to make money from this